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In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]

3.5 Quality assessment The quality assessment based on the JBI Case Report Checklist showed an overall low risk of bias in 20 cases included in the 18 studies

Food sits in your stomach much longer than it normally would

Clinical trials suggest a mean weight reduction of approximately 23 kg over 812 weeks, but study quality is generally poor and long-term outcomes are unknown